They can also go on a FAT32 formatted USB hard drive, it doesn't need to be on the SD card. For multi disk just add a folder and change the name to game. Without counting multiple versions of Wii & GameCube games you can fit 99% of the Wii & GameCube games onto a 4TB hard drive using Wii's in. If you want to launch it via USB L-GX, then you have to put the games like SD/games/ Programs don't care what you put here you can put anything/game.iso. Make sure not to double up in the extension if you have hidden extensions, because will not work and many people make this mistake without realizing it. You'll use Nintendot to run the GameCube games either directly or through one of the loaders. You'll then want to place the game ISO into a 'games' directory in the root of your SD or USB, make a directory for the game with it's name and code and then inside of that rename the game ISO to game, as in game.iso.
This way you won't run into any problems in using the wrong program to trim it and while most games will work after being trimmed there are a few that need to be the full ISO to work. There are a couple of programs that will trim their size down, but if you have a large enough hard drive or only playing a few games I'd recommend just leaving them as the full ISO.
No, this will not work with GameCube games.
